姓 名:尹琦
重庆医科大学公共卫生学院,副研究员,硕士研究生导师
Email:yinqibio@cqmu.edu.cn
研究方向:人类肠道菌群与健康;宏基因组;特殊生境厌氧微生物分类;病原菌生物膜感染
长期从事潜在厌氧益生菌的分离和鉴定,病原菌泛基因组耐药分析、肠道菌群宏基因组分析菌群互作,探究人类肠道菌群互作如何影响病原菌定殖、感染发生和耐药进展。以一作或通讯在Nature Microbiology、Journal ofAntimicrobial Chemotherapy、Biofouling等杂志发表论文。主持国家自然科学基金、国家博士后基金、重庆市科技局科研项目多项。并受邀在剑桥大学、牛津大学以及美国微生物学会年会(ASM 2024)进行相关课题的大会口头报告。
学习及工作经历
-2022.12-2025.12国家留学基金委公派面上项目,剑桥大学,访问学者
-2020.10至今任职于重庆医科大学公共卫生学院,卫生检验教研室,副研究员
-2018.11-2020.09任四川大学华西医院生物治疗国家重点实验室专职博士后/助理研究员
-2016.10-2018.10任深圳大学专职博士后,香港科技大学访问学者
-2016年获中国科学院大学理学博士学位
-2012年获中国海洋大学微生物学学术型硕士学位
-2010年获中国海洋大获生物科学理学学士学位
主持科研项目
近5年代表性学术论文
Yin Q, da Silva, A.C., Zorrilla, F. et al. Ecological dynamics of Enterobacteriaceaein the human gut microbiome across global populations. Nature Microbiology (2025) .https://doi.org/10.1038/s41564-024-01912-6. (中科院JCR一区,IF = 20.5)
Liu X-R, et al.,Yin Q*.Lactobacillusfrom fermented bamboo shoots prevents inflammation in DSS-induced colitis mice via modulating gut microbiome and serum metabolites.Food Science and Human Wellness, 2024, 13(5): 2833-2846. (中科院JCR一区,TOP,IF = 5.6). *Correspondence
Nie H, et al.,Yin Q*. Prodigiosin derived from chromium-resistantSerratiasp. prevents inflammation and modulates gut microbiota homeostasis in DSS-induced colitis mice.International Immunopharmacology, 2023, doi: 10.1016/j.intimp.2023.109800. (中科院JCR二区,IF = 5.71) *Correspondence
Gao M, Duan X, Liu X-R, Luo S, Tang S, Nie H, Yan J, Zou Z, Chen C,Yin Q* and Qiu J*.Modulatory effects of Huoxiang Zhengqi oral liquid on gut microbiome homeostasis based on healthy adults and antibiotic-induced gut microbial dysbiosis mice model.Frontiers in Pharmacology, 2022, 13:841990.(中科院JCR一区,2021IF=5.99)*Correspondingauthor
Liu Y#, Qiu Y#,Yin Q#, Li X, Bai Q, Li Y, Xiao H*. iTRAQ-based quantitative proteomic reveals proteomic changes in Serratia sp. CM01 and mechanism ofCr(Ⅵ) resistance.Ecotoxicology and Environmental Safety, 2021 228:112899.(中科院JCR一区,2021 IF 7.13)#Co-firstauthor
Li X#,Yin Q#, Gu R,etal. Effects of exogenous sulfate on the chromium(VI) metabolism of chromium(VI)-resistant engineered strains.Ecotoxicology and Environmental Safety,2021,228:112984.(中科院JCR一区,2021 IF 7.13)#Co-firstauthor
Yin Q, Liang J, Zheng X,etal. Description ofAlgibacter onchidiisp. nov., a symbiotic bacterium isolated from a marine invertebrate, by phenotypic, phylogenetic and comparative genomic analyses.Int J Syst Evol Microbiol, 2021, 71(11): 005102. (微生物新种专刊,2020IF=2.747)
Yin Q, Wu S, Wu L,etal.A novelin silicoantimicrobial peptide DP7 combats MDRPseudomonas aeruginosaand related biofilm infections.Journal of Antimicrobial Chemotherapy,2020, 75(11):3248-3259.(中科院JCR一区/医学TOP,2020 IF= 5.79)
Yin Q, Liang J, Zhang W,etal. Butenolide, a marine derived broad-spectrum antibiofilm agent against both Gram-positive and Gram-negative pathogenic bacteria.Marine Biotechnology,2019, 21(1):88-98.(中科院JCR二区,3-Year IF 3.619)