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周莉
作者: 发布时间: 2022-10-29 14:07 浏览次数:

姓名:周莉

重庆医科大学公共卫生学院,教授,博士生导师(流行病与卫生统计学)

流行病学教研室主任,研究生第一党支部书记

E-Mail:zhouli@cqmu.edu.cn

研究方向:冠心病与乙肝的分子流行病学研究、慢性病环境流行病学研究

学习及工作经历:

2001.9-2006.6华中科技大学同济医学院公共卫生学院预防医学专业;2006.9-2011.6华中科技大学同济医学院公共卫生学院劳动卫生与环境卫生学博士学位,导师邬堂春院士;

2008.11-2009.2加拿大Laval大学访问学习;

2017.6-2018.7美国辛辛那提大学医学院访问学习;

2011.7年至今 重庆医科大学公共卫生学院流行病学教研室,现任流行病学教研室主任。

主持科研项目:

1.国家自然科学基金面上项目,脂蛋白相关lncRNA及其遗传变异通过参与炎性反应导致冠心病发生发展的分子流行病学研究,81773519,2018-01至2021-12,65万元;

2.国家自然科学基金青年基金项目,血脂相关基因的遗传变异与冠心病易感性的关联研究,81202274,2013年1月-2015年12月,23万元

3.重庆市自然科学基金项目,宿主遗传变异对乙肝高危儿童免疫接种后病毒突破的影响及机制,2014.07-2017.06,5万元

4.重庆市渝中区科技局项目,基于临床大数据的乙肝肝硬化患者抗病毒治疗的结局预测模型构建,2021.11-2024.9,5万元

5.重庆医科大学智慧医学项目,基于医疗大数据和全基因组的乙肝病人肝纤维化的预测模型研究,2020.9-2022.11,3万元

6.重庆医科大学优秀青年学者基金项目,宿主遗传变异对乙肝高危儿童免疫接种后病毒突破的影响及机制,2013.9-2015.11,10万元

第一/通讯作者发表论文:

[1]Zhou L#, Ren JH#, Cheng ST#, Xu HM, Chen WX, Chen DP, Wong VKW, Law BYK, Liu Y, Cai XF, Tang H, Yu HB, Hu JL, Hu Y, Zhou HZ, Ren F, He L, Hu ZW, Jiang H, Xu HY, Huang AL*, Chen J*. A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A.Hepatology.2019;69(5):1885-1902.

[2]Chen H, Cheng Z, Li M, Luo P, Duan Y, Fan J, Xu Y, Pu K,Zhou L*. Ambient Air Pollution and Hospitalizations for Ischemic Stroke: A Time Series Analysis Using a Distributed Lag Nonlinear Model in Chongqing, China.Front Public Health. 2022 Jan 18;9:762597.

[3]Zhuo Y, Yang Y, Zhang M, Xu Y, Chen Z, Mu L, Tang X, Zhong Z, Chen J,Zhou L*. Single Nucleotide Polymorphisms in IFN-gamma Signaling Pathway Associated with Risk of Hepatitis B Virus Infection in Chinese Children. Can J Infect Dis Med Microbiol. 2020:8121659.

[4]Li M, Xu Y, Pu K, Fan J, Cheng Z, Chen H,Zhou L*. Genetic polymorphisms of chemokine (C-X-C motif) ligand 10 gene associated with hepatitis B virus infection in a Chinese Han population. Int Immunopharmacol. 2021 Sep;98:107888.

[4] Wang L, Chen J, Zeng Y, Wei J, Jing J, Li G, Su L, Tang X, Wu T,Zhou L*. Functional Variant in the SLC22A3-LPAL2-LPA Gene Cluster Contributes to the Severity of Coronary Artery Disease. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1989-96.

[5] Fan J#, Huang X#, Chen J, Cai Y, Xiong L, Mu L,Zhou L*. Host Genetic Variants in HLA Loci Influence Risk for Hepatitis B Virus Infection in Children. Hepat Mon. 2016;16(8):e37786.

[6] Fan J#, Cai Y#, Huang X, Wang Y, Mu L*,Zhou L*. Variations in IL-1R1 Gene Influence Risk for Hepatitis B Virus Infection of Children in a Han Chinese population. Int J Infect Dis. 2017;55:45-50.

[7] Xu Y#, Zhuo Y#, Ye M#, Li M, Tang X,Zhou L*. Association study of genetic variants at TTC32‐WDR35 gene cluster with coronary artery disease in Chinese Han population.J Clin Lab Anal. 2021 Feb;35(2):e23594.

[8] Jing J, Su L, Zeng Y, Tang X, Wei J, Wang L,Zhou L*. Variants in 9p21 Predicts Severity of Coronary Artery Disease in a Chinese Han Population. Ann Hum Genet. 2016 Sep;80(5):274-81.

[9] Zhuo Y#, Yang Y#, Zhang M, Xu Y, Chen Z, Mu L, Tang X, Zhong Z, Chen J,Zhou L*. Single Nucleotide Polymorphisms in IFN-gamma Signaling Pathway Associated with Risk of Hepatitis B Virus Infection in Chinese Children. Can J Infect Dis Med Microbiol. 2020:8121659.

[10] Li M, Zhuo Y, Xu Y, Chen H, Cheng Z,Zhou L*. Genetic Association of Interleukin-6 Polymorphism (rs1800796) with Chronic Hepatitis B Virus Infection in Chinese Han Population. Viral Immunol. 2021 May;34(4):267-272.

[11] Wang L, Jing J, Fu Q, Tang X, Su L, Wu S, Li G,Zhou L*. Association study of genetic variants at newly identified lipid gene trib1 with coronary heart disease in chinesehan population. Lipids in health and disease. 2015;14:46.

[12] Ren JH#, Chen X#,Zhou L#, Tao NN, Zhou HZ, Liu B, Li WY, Huang AL*, Chen J*. Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression. PLoS One. 2016 Mar 7;11(3):e0150961.

[13] Li L#, He M#,Zhou L#, Miao X, Wu F, Huang S, Dai X, Wang T, Wu T. A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response. J Biol Chem. 2015 Feb 27;290(9):5328-40.

[14] Fu Q, Tang X, Chen J, Su L, Zhang M, Wang L, Jing J,Zhou L*.Effects of polymorphisms in apoa4-apoa5-znf259-bud13 gene cluster on plasma levels of triglycerides and risk of coronary heart disease in a Chinese Han population. PloS one. 2015;10: e0138652.

[15]黄歆,周莉*,牟李红,范捷,蔡一玲.乙型肝炎高危儿童免疫预防效果及乙肝病毒母婴传播影响因素分析.中国当代儿科. 2016;18(5):410-414.

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